Price range: $40.00 through $466.00 / 10 Vials
Retatrutide is a pioneering synthetic peptide and a triple hormone receptor agonist. By simultaneously activating the GLP-1, GIP, and Glucagon (GCGR) receptors, it achieves a synergistic effect on metabolic regulation that far exceeds earlier mono or dual-agonist therapies. In clinical research settings, Retatrutide is studied for its profound impact on weight reduction, glycemic control, and the resolution of non-alcoholic fatty liver disease (NAFLD), representing the next generation of metabolic intervention.
Amino Acid Sequence Tyr-Aib-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-Aib-Leu-Asp-Lys-Ile-Ala-Gln-Lys(C18)-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2
Molecular Formula$C_{221}H_{342}N_{52}O_{68}$ (Approximate)
Molecular Weight 4731.3 g/mol
PubChem CID 167451124
CAS Number 2381089-83-2
Vial Size 3ml (Standard concentrations: 5mg, 10mg, or 15mg per vial)
Contents Lyophilized powder, white/off-white color
| Size | 100mg, 60mg, 50mg, 40mg, 30mg, 20mg, 15mg, 10mg, 5mg |
|---|---|
| Mechanism of Action | GLP-1 & GIP Dual Incretin Effect: Similar to Tirzepatide, it enhances insulin secretion in a glucose-dependent manner and significantly slows gastric emptying, leading to prolonged satiety and reduced caloric intake (α). Glucagon (GCGR) Activation: Unlike earlier peptides, Retatrutide adds glucagon receptor agonism, which directly increases energy expenditure and stimulates thermogenesis in the liver and adipose tissues (β). Triple-Path Synergism: The integration of the GCGR component allows for a "fat-burning" signal that complements the "appetite-suppression" signals of GLP-1 and GIP, resulting in more rapid lipolysis (fat breakdown) in research models. Metabolic Flexibility: It promotes improved insulin sensitivity and helps stabilize blood glucose levels, while simultaneously targeting intra-hepatic fat, making it a subject of intense study for metabolic syndrome (γ). |
| Storage & handling | Storage:Store the lyophilized vial in a cool, dry area protected from direct sunlight. |
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