Product details
\nAmino Acid Sequence\uff1aAc-Lys-Lys-Thr-Glu-Thr-Gln (Ac-LKKTETQ)
\nMolecular Formula\uff1aC\u2083\u2088H\u2086\u2088N\u2081\u2080O\u2081\u2084
\nMolecular Weight\uff1a889.02 g\/mol
\nPubChem CID\uff1a62707662
\nCAS Number\uff1a885340-08-9
\nContents\uff1aLyophilized powder, white\/off-white color<\/p>\n","protected":false},"excerpt":{"rendered":"
TB-500 (TB500 or Thymosin \u03b2-4 Active Fragment) is a synthetic heptapeptide corresponding to the N-terminal actin-binding domain of endogenous Thymosin \u03b2-4. It modulates cytoskeletal dynamics by sequestering G-actin monomers and promoting localized F-actin polymerization, thereby enhancing cellular motility and migration. TB-500 upregulates angiogenic growth factors (e.g., VEGF, FGF-2) via MAPK\/ERK and PI3K\/Akt signaling, driving neovascularization in ischemic or injured tissues. Concurrently, it attenuates pro-inflammatory cytokines (TNF-\u03b1, IL-6) through NF-\u03baB inhibition, creating a reparative microenvironment. In in vitro and rodent models, these combined actions support accelerated tissue regeneration, angiogenesis, and reduced inflammatory damage.<\/p>\n","protected":false},"featured_media":615,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[68,21],"product_tag":[],"class_list":{"0":"post-612","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-anti-aging-longevity","7":"product_cat-repair-anti-inflammatory","8":"product_shipping_class-peptide","10":"first","11":"instock","12":"shipping-taxable","13":"purchasable","14":"product-type-variable","15":"has-default-attributes"},"_links":{"self":[{"href":"https:\/\/www.genixpep.com\/index.php\/wp-json\/wp\/v2\/product\/612","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.genixpep.com\/index.php\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/www.genixpep.com\/index.php\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/www.genixpep.com\/index.php\/wp-json\/wp\/v2\/comments?post=612"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.genixpep.com\/index.php\/wp-json\/wp\/v2\/media\/615"}],"wp:attachment":[{"href":"https:\/\/www.genixpep.com\/index.php\/wp-json\/wp\/v2\/media?parent=612"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/www.genixpep.com\/index.php\/wp-json\/wp\/v2\/product_brand?post=612"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/www.genixpep.com\/index.php\/wp-json\/wp\/v2\/product_cat?post=612"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/www.genixpep.com\/index.php\/wp-json\/wp\/v2\/product_tag?post=612"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}